منابع مشابه
How Old Is the Genetic Code ? Statistical Geometry of tRNA Provides Answer MANFRED EIGEN
The age of the molecular organization of life as expressed in the genetic code can be estimated from experimental data. Comparative sequence analysis of transfer RNA by the method of statistical geometry in sequence space suggests that about one-third of the present wansfer RNA sequence divergence was present at the urkingdom level about the time when archaebacteria separated from eubacteria. I...
متن کاملRigorous mathematical analysis of the quasispecies model: From Manfred Eigen to the recent developments
We review the major progress in the rigorous analysis of the classical quasispecies model that usually comes in two related but different forms: the Eigen model and the Crow–Kimura model. The model itself was formulated almost 50 years ago, and in its stationary form represents an easy to formulate eigenvalue problem. Notwithstanding the simplicity of the problem statement, we still lack full u...
متن کاملManfred Kayser
restaurants. Japan consumes about 80 per cent of Pacific and Atlantic bluefin tuna. The country has been accused of stifling efforts to enhance protection of the tuna stocks. In negotiations last year, a bid by Monaco, backed by several other European countries, to introduce a ban on commercial fishing of Atlantic bluefin tuna failed because of perceived support from several smaller nations for...
متن کاملBibliography Manfred Jeusfeld
• Process-Data Diagrams (PDDs) are a popular technique to represent method fragments and their recombination to new adapted method specifications. It turns out that PDDs are at odds with a strict separation of MOF/MDA abstraction levels as advocated by MOF/MDA. We abandon the restriction and specify PDDs by a metametamodel that supports both process and product parts of PDDs. The instantiation ...
متن کاملManfred Droste 1 and Dietrich Kuske
Weighted automata are classical finite automata in which the transitions carry weights. 7 These weights may model quantitative properties like the amount of resources needed for executing 8 a transition or the probability or reliability of its successful execution. Using weighted automata, 9 we may also count the number of successful paths labeled by a given word. 10 As an introduction into thi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Angewandte Chemie
سال: 2019
ISSN: 0044-8249,1521-3757
DOI: 10.1002/ange.201904708